Have you ever used Hotels.com to book a vacation package with flights and car rental?

This might sound like an odd question to ask but basically, I want to go on a long trip on my own. My itinerary includes a short road trip, traveling by plane, and staying at a hotel. A whole package, pretty much.

I was told that Hotels.com offers all that I need, but I want to ask if somebody has done something similar. How did it go? Did you have any issues booking all the things you needed? Do you think it is a good idea to book vacation packages with flights and car rentals from Hotels.com, or should I book everything separately instead?